James P. Sethna

This study investigates shear strain stiffening in cartilage, showing it results from a mechanical phase transition between bending- and stretching-dominated modes, influenced by collagen concentration and compression.

The paper uses a geometry-aware autoencoder to analyze hippocampal activity in mice, revealing a small-world network structure that enables both local fidelity and global searchability in cognitive maps.

The paper shows that adding small molecules to biomolecular condensates reduces their partition coefficients to physiological levels, revealing changes in their material properties and behavior.

This study investigates the torsional mechanics of circular DNA, showing that underwound DNA has a torque near the melting threshold and equal force/torque distribution, with implications for DNA-protein interactions.