Author

Yuanxiao Tang

Shanghai Jiao Tong UniversityORCID 0000-0002-5153-1632Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 3 Research Focus:gene regulatory network inference· 3 Organism:human· 3 Assay:ATAC-seq· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

Qiang WuiD· 3 shared Haiyan Huang· 1 shared Honglin XuiD· 1 shared Leyang WangiD· 1 shared Lian LiuiD· 1 shared Lin‐Tai DaiD· 1 shared Tianjie LiiD· 1 shared Yan ZhangiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 15 mutual co-author links

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3 shared papersMolecular Biology

Qiang WuORCID

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3 papers

Recent·Most cited

WAVE2 and REST/NRSF Regulate Clustered Gene Expression by Maintaining Heterochromatin Organization

Leyang Wang, Yuanxiao Tang, Tianjie Li, Haiyan Huang, Qiang Wu

This study shows WAVE2 and REST/NRSF regulate clustered gene expression by maintaining heterochromatin organization through chromatin dynamics and spatial reorganization.

The FASEB Journal · Aug 18, 2026Peer-reviewedMolecular Biology

A negatively-charged region within carboxy-terminal domain maintains proper CTCF DNA binding

Lian Liu, Yuanxiao Tang, Yan Zhang, Qiang Wu

The paper identifies a negatively-charged region in CTCF's C-terminal domain that weakens DNA binding and chromatin accessibility through an autoinhibitory mechanism.

iScience · Nov 22, 2024Peer-reviewedGenetics

Mechanism of REST/NRSF Regulation of Clustered Protocadherin Alpha Genes

Yuanxiao Tang, Zhilian Jia, Honglin Xu, Lin‐Tai Da, Qiang Wu

This study investigates how REST/NRSF regulates clustered protocadherin genes by forming directional base-specific interactions with NRSEs and altering enhancer-promoter interactions.

Nucleic Acids Research · Mar 26, 2021Peer-reviewedMolecular Biology