Author

Haiyan Huang

Shanghai Jiao Tong University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Bioinformatics· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:batch correction / integration· 1 Assay:ChIP-seq· 1 Approach:deep learning· 1

Frequent Co-Authors

Qiang WuiD· 2 shared A. Sina BooeshaghiiD· 1 shared Aaron StreetsiD· 1 shared Guojun HouiD· 1 shared Huaijin Feng· 1 shared Jase GehringiD· 1 shared Jin ZhuiD· 1 shared Juliana J. LeeiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersMolecular Biology

Qiang WuORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Denoising single-cell ATAC-seq data with Shannon entropy

Shiyi Yang, Kevin An, Juliana J. Lee, Jase Gehring, A. Sina Booeshaghi, Haiyan Huang, Aaron Streets

This paper introduces a Shannon entropy-based method to filter high-quality nuclei in scATAC-seq data, improving signal-to-noise ratio and downstream analysis reliability.

bioRxiv · Oct 23, 2026 · PreprintBioinformatics

WAVE2 and REST/NRSF Regulate Clustered Gene Expression by Maintaining Heterochromatin Organization

Leyang Wang, Yuanxiao Tang, Tianjie Li, Haiyan Huang, Qiang Wu

This study shows WAVE2 and REST/NRSF regulate clustered gene expression by maintaining heterochromatin organization through chromatin dynamics and spatial reorganization.

The FASEB Journal · Aug 18, 2026Peer-reviewedMolecular Biology

DNA sequence quantitatively encodes CTCF-binding affinity at genome scale

Zihang Yin, Yefan Wang, Guojun Hou, Yuqiao Chen, Huaijin Feng, Jin Zhu, Yufan Xie, Ruoxi Wang, Zhiyu Zhang, Tao Wu, Haiyan Huang, Sheila Q. Xie, Wuming Wang, Wenchao Gu, Qiang Wu, , Ya Guo

The paper experimentally measures CTCF-binding affinity across 276,765 human DNA sequences and develops a deep learning model to predict and interpret binding strength based on sequence features.

bioRxiv · Jan 5, 2026 · PreprintGenomics