Joe G. Greener

Molecular mechanism of Mad2 conformational conversion promoted by the Mad2-interaction motif of Cdc20

This study elucidates how the Cdc20MIM induces Mad2 conformational conversion by transiently exposing a binding site and facilitating structural changes.

Fast protein structure searching using structure graph embeddings

The paper introduces Progres, a method for fast protein structure searching using graph neural networks, achieving accuracy comparable to existing methods with rapid query times.

Differentiable molecular simulation can learn all the parameters in a coarse-grained force field for proteins

This paper demonstrates using automatic differentiation to train a coarse-grained force field for proteins, achieving stable structure and dynamics.

Using AlphaFold for Rapid and Accurate Fixed Backbone Protein Design

The paper uses AlphaFold to design novel proteins with fixed backbones, showing agreement between predicted structures and desired backbones.

Ultrafast end-to-end protein structure prediction enables high-throughput exploration of uncharacterised proteins

The paper introduces an ultrafast protein structure prediction method that directly outputs backbone coordinates from MSAs, enabling rapid modeling of uncharacterized proteins.

Prediction of inter-residue contacts with DeepMetaPSICOV in CASP13

The paper describes the development and application of DeepMetaPSICOV for contact prediction in CASP13, highlighting improvements in alignment generation and performance.