Author

Alexander J. Pfeil

University of North Carolina at Chapel HillORCID 0000-0002-5159-019XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Andrea M. GazzoiD· 1 shared Christopher A. Febres‐AldanaiD· 1 shared Elisa de StanchinaiD· 1 shared Inna KhodosiD· 1 shared Jenna-Marie DixiD· 1 shared Juan Luis Gomez MartiiD· 1 shared Kathryn Cecilia ArbouriD· 1 shared Leo GiliiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

Andrea M. GazzoORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

RRAS and RRAS2 mutations are recurrent oncogenic drivers in lung cancer and are sensitive to the pan-RAS inhibitor RMC-6236

Alexander J. Pfeil, Tom Zhang, Ryan Cheng, Marissa S. Mattar, Juan Luis Gomez Marti, Leo Gili, Rachel Lai, Inna Khodos, Rohan P Master, Jenna-Marie Dix, Andrea M. Gazzo, Kathryn Cecilia Arbour, Elisa de Stanchina, Christopher A. Febres‐Aldana, Marc Ladanyi, , Romel Somwar

This study identifies RRASQ87L and RRAS2Q72L mutations as recurrent oncogenic drivers in lung cancer and shows sensitivity to the pan-RAS inhibitor RMC-6236.

Clinical Cancer Research · Jan 16, 2026Peer-reviewedCancer Biology