Structure-based development of new cyclic compoundstargeting PSD-95 PDZ3 domain.
Mandar T. Naik, Nandita M. Naik, Ye Hu, Szu‐Huan Wang, John J. Marshall
The paper develops new cyclic compounds targeting the PSD-95 PDZ3 domain through structure-based design, achieving up to 7-fold stronger affinity than a prototype compound.
FEBS Letters · Oct 31, 2023Peer-reviewedMolecular Biology