Author

RALPH THEO SCHERMULY

Justus-Liebig-Universität GießenORCID 0000-0002-5167-6970Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cell Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:CUT&Tag· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Astrid WeißiD· 2 shared Aileen Schmidt· 1 shared Anna Evgenevna Kuleshova· 1 shared Arjang RuhparwariD· 1 shared Axel WeberiD· 1 shared Baktybek K. KojonazaroviD· 1 shared Bernd NiemanniD· 1 shared Carola VossiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCell Biology

Astrid WeißORCID

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3 papers

Recent·Most cited

iPSC modeling of pulmonary arterial hypertension to uncover pathomechanisms and unrecognized modes of action of sotatercept

Aileen Schmidt, Laurien Czichon, Leonie Malhofer, Gioia Bartsch, Clara Plötner, Yuepeng Wang, Carola Voss, Anna Evgenevna Kuleshova, Tim Kohrn, Julia Baldauf, Astrid Weiß, RALPH THEO SCHERMULY, Arjang Ruhparwar, Jan C. Kamp, Marius M. Hoeper, , Ruth Olmer

This study uses patient-derived iSMCs to uncover new mechanisms of PAH and sotatercept's effects beyond its known anti-proliferative actions.

bioRxiv · Oct 30, 2026 · PreprintCell Biology

Differential multi-omics analysis of pulmonary arterial hypertension microvascular endothelial cells for differential drug response

Pauline Hiort, Astrid Weiß, Janina Krentz, RALPH THEO SCHERMULY, Harm Jan Bogaard, Tim Conrad, Robert Szulcek, Katharina Baum

The paper uses a multi-omics framework to analyze PAH endothelial cells and identifies kinase-related alterations and potential drug targets.

bioRxiv · Jul 16, 2026 · PreprintBioinformatics

A common gene signature of the right ventricle in failing rat and human hearts

Liane Jurida, Sebastian Werner, Fabienne Knapp, Bernd Niemann, Ling Li, Dimitri Grün, Stefanie Wirth, Axel Weber, Knut Beuerlein, Christoph Liebetrau, Christoph B. Wiedenroth, Stefan Guth, Baktybek K. Kojonazarov, Leili Jafari, Norbert Weißmann, , Michael Kracht

The paper identifies a conserved gene signature associated with right ventricular failure in both rat and human hearts through transcriptomic analysis and validation.

Nature Cardiovascular Research · Jul 5, 2024Peer-reviewedGenomics