Author

Michael Kracht

Justus-Liebig-Universität GießenORCID 0000-0002-8501-043XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

Axel WeberiD· 3 shared Christin Mayr‐Buro· 2 shared Hendrik Weiser· 2 shared Jochen WilhelmiD· 2 shared Johanna Meier‐SoelchiD· 2 shared Liane Jurida· 2 shared Marek BartkuhniD· 2 shared Michael Lienhard SchmitziD· 2 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersSystems Biology

Axel WeberORCID

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3 papers

Recent·Most cited

PERK inhibition rewires translational and CMGC protein kinase networks into an antiviral state

Mohammed Samer Shaban, Hendrik Weiser, Axel Weber, Johanna Meier‐Soelch, Franziska Dort, Christin Mayr‐Buro, Michael Poppe, Nadja Karl, Jochen Wilhelm, John Ziebuhr, Uwe Linne, Michael Kracht

The paper shows that inhibiting PERK rewires host kinase networks to create an antiviral state during coronavirus infection.

bioRxiv · Oct 8, 2025 · PreprintSystems Biology

The proximity-based protein interaction landscape of the transcription factor p65 NF-kappaB/RELA and its gene-regulatory logics

Lisa Leib, J. Unternaehrer Juli, Liane Jurida, Christin Mayr‐Buro, Jasmin Priester, Hendrik Weiser, Stefanie Wirth, Simon Hanel, Daniel Heylmann, Axel Weber, Michael Lienhard Schmitz, Argyris Papantonis, Marek Bartkuhn, Jochen Wilhelm, Uwe Linne, , Michael Kracht

The paper identifies >350 p65/RELA interactors and reveals gene regulatory networks controlled by RELA and its interactors in the IL-1 response.

EMBO Reports · Jan 3, 2025Peer-reviewedMolecular Biology

A common gene signature of the right ventricle in failing rat and human hearts

Liane Jurida, Sebastian Werner, Fabienne Knapp, Bernd Niemann, Ling Li, Dimitri Grün, Stefanie Wirth, Axel Weber, Knut Beuerlein, Christoph Liebetrau, Christoph B. Wiedenroth, Stefan Guth, Baktybek K. Kojonazarov, Leili Jafari, Norbert Weißmann, , Michael Kracht

The paper identifies a conserved gene signature associated with right ventricular failure in both rat and human hearts through transcriptomic analysis and validation.

Nature Cardiovascular Research · Jul 5, 2024Peer-reviewedGenomics