Synthetic BiologybioRxivPreprint
Integration of microbial and chemical synthesis for the efficient production of plitidepsin, a promising anticancer and antiviral agent
Haili Zhang, Zhen Hui, Mingwei Cai…·Xiaoyu Tang
This paper combines microbial and chemical synthesis to efficiently produce plitidepsin, achieving high yields and new analogues with anticancer and antiviral activities.