Author

Ching‐Hua Lu

China Medical UniversityORCID 0000-0002-5191-5089Unclaimed ORCID profile · follow to get notified of new preprints

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1

Frequent Co-Authors

Andrea MalaspinaiD· 3 shared Pietro FrattaiD· 3 shared Linda GreensmithiD· 2 shared Vittoria LombardiiD· 2 shared Adrian M. IsaacsiD· 1 shared Ahuva NissimiD· 1 shared Alessandro BombaciiD· 1 shared Amanda HeslegraveiD· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersNeuroscience

Andrea MalaspinaORCID

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3 papers

Recent·Most cited

Circulating miR-181 is a prognostic biomarker for amyotrophic lateral sclerosis

Iddo Magen, Nancy‐Sarah Yacovzada, Eran Yanowski, Anna M. L. Coenen-Stass, Julian Großkreutz, Ching‐Hua Lu, Linda Greensmith, Andrea Malaspina, Pietro Fratta, Eran Hornstein

The paper identifies miR-181 as a prognostic biomarker in ALS, showing it predicts higher mortality risk and improves prognosis prediction when combined with NfL.

Nature Neuroscience · Oct 28, 2021Peer-reviewedNeuroscience

Immune reactivity to neurofilaments and dipeptide repeats in ALS progression

Fabìola Puentes, Vittoria Lombardi, Ching‐Hua Lu, Özlem Yildiz, Angray S. Kang, Ahuva Nissim, Pietro Fratta, Adrian M. Isaacs, Yoana Bobeva, Andrea Malaspina

The paper tests antibody and immune-complex responses to neurofilaments and dipeptide-repeats as biomarkers for ALS progression and stratification.

bioRxiv · Feb 25, 2020 · PreprintNeuroscience

Plasma pNfH differentiate SBMA from ALS

Vittoria Lombardi, Alessandro Bombaci, Luca Zampedri, Ching‐Hua Lu, Bilal Ahmad Malik, Henrik Zetterberg, Amanda Heslegrave, Carlo Rinaldi, Linda Greensmith, Michael G. Hanna, Andrea Malaspina, Pietro Fratta

The paper measures plasma pNfH levels in SBMA and ALS patients, finding no increase in SBMA but a significant increase in ALS, suggesting pNfH could differentiate the two diseases.

bioRxiv · Feb 14, 2019 · PreprintNeuroscience