Molecular BiologyMolecular CellPeer-reviewed
Structural Basis for Cas9-Directed Spacer Acquisition in Type II-A CRISPR-Cas Systems
Zhaoxing Li, Yutao Li, Jianping Kong…·Yibei Xiao
This study reveals the structural dynamics of Cas9-mediated spacer acquisition in Type II-A CRISPR-Cas systems through cryo-EM analysis of the Cas9-Csn2-Cas1-Cas2 complex.
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