Molecular BiologybioRxivPreprint
Substrate-induced asymmetry coordinates lipoprotein handover and abaucin trapping in Acinetobacter baumannii LolDF
DOI 10.64898/2026.10.30.762977
Author
Zhaoxing Li
China Pharmaceutical UniversityORCID 0000-0002-6928-9856Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2024-2026 · peak 3/yrCo-Author Collaboration Network
10 top collaborators · 42 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship5 papers
Recent·Most cited
- MicrobiologybioRxivPreprint
Avs2 drives non-canonical tetrameric assembly of trypsin-like domain for anti-phage defense
Lijie Guo, Pingping Huang, Wenhui Liu…·Meirong Chen
The paper elucidates the molecular mechanism of the Avs2-trypsin-MBL system, revealing how phage terminase recognition triggers tetramerization and activation of the system for anti-phage defense.
DOI 10.64898/2026.08.25.746987 - Molecular BiologyMolecular CellPeer-reviewed
Structural Basis for Cas9-Directed Spacer Acquisition in Type II-A CRISPR-Cas Systems
Zhaoxing Li, Yutao Li, Jianping Kong…·Yibei Xiao
This study reveals the structural dynamics of Cas9-mediated spacer acquisition in Type II-A CRISPR-Cas systems through cryo-EM analysis of the Cas9-Csn2-Cas1-Cas2 complex.
3 citationstop 4% - BiochemistrybioRxivPreprint
The anti-phage mechanism of a widespread trypsin-MBL module
Pingping Huang, Jingxian Liu, Lijie Guo…·Meirong Chen
This study identifies a trypsin-MBL module as a bacterial immune effector that uses proteolytic activation to enable DNase activity against invading nucleic acids while preventing self-toxicity.
- Molecular BiologybioRxivPreprint
The mechanism of bacterial defense system DdmDE from Lactobacillus casei
Pingping Huang, Purui Yan, Lijie Guo…·Meirong Chen
This study reveals the mechanism of the DdmDE system in Lactobacillus casei, showing how it degrades plasmids through a guided helicase-nuclease activity.
DOI 10.1101/2024.10.09.617351