Author

Xin Chen

Loma Linda UniversityORCID 0000-0002-5208-2154Unclaimed ORCID profile · follow to get notified of new preprints

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Xin Chen20 papers · Campbell University

Biology Disciplines

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Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:benchmark study· 2 Research Focus:benchmarking· 2 Assay:scRNA-seq· 2 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrew A. FarmeriD· 2 shared Bao Quoc TraniD· 2 shared Charles WangiD· 2 shared Malcolm C. MoosiD· 2 shared Wanqiu CheniD· 2 shared Wenming XiaoiD· 2 shared Yongmei ZhaoiD· 2 shared Zhaowei YangiD· 2 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioinformatics

Andrew A. FarmerORCID

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2 papers

Recent·Most cited

A Multi-center Cross-platform Single-cell RNA Sequencing Reference Dataset

Xin Chen, Zhaowei Yang, Wanqiu Chen, Yongmei Zhao, Andrew A. Farmer, Bao Quoc Tran, Vyacheslav A. Furtak, Malcolm C. Moos, Wenming Xiao, Charles Wang

The paper presents a multi-center cross-platform scRNA-seq reference dataset for benchmarking bioinformatics methods across different platforms and centers.

Scientific Data · Feb 2, 2021Peer-reviewedBioinformatics

A Comprehensive Multi-Center Cross-platform Benchmarking Study of Single-cell RNA Sequencing Using Reference Samples

Wanqiu Chen, Yongmei Zhao, Xin Chen, Zhaowei Yang, Xiaojiang Xu, Yingtao Bi, Vicky Chen, Jing Li, Hannah Choi, Ben Ernest, Bao Quoc Tran, Monika Mehta, Parimal Kumar, Andrew A. Farmer, Alain A. Mir, , Charles Wang

This study benchmarks scRNA-seq reproducibility across platforms and pipelines, finding that batch correction methods significantly affect results.

Nature Biotechnology · Dec 21, 2020Peer-reviewedGenomics