Author

Haruki Higashimori

Brown UniversityORCID 0000-0002-5212-5249Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Alessandra Tamashiro OrregoiD· 1 shared Brian C. KavanaughiD· 1 shared Carin M. PapendorpiD· 1 shared Carrie R. Best· 1 shared Christina Schin· 1 shared Cosmo A. PieplowiD· 1 shared Dan Cox· 1 shared Duyu A. NieiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Alessandra Tamashiro OrregoORCID

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2 papers

Recent·Most cited

Mutations in ASH1L cause a neurodevelopmental disorder with sex differences in epilepsy and autism

Carin M. Papendorp, Elizabeth Nolan, Haruki Higashimori, Megha Jhanji, Luis Goicouria, Cosmo A. Pieplow, Kirsten Whitley, Steven Defreitas, Jennifer Elacio, Duyu A. Nie, Brian C. Kavanaugh, Carrie R. Best, Sofia B. Lizarraga, Judy Shih-Hwa Liu

This study identifies ASH1L mutations causing a neurodevelopmental disorder with sex-specific effects on epilepsy and autism in mice and humans.

bioRxiv · Feb 21, 2025 · PreprintNeuroscience

Astroglial FMRP modulates synaptic signaling and behavior phenotypes in FXS mouse model

Shan‐Xue Jin, Haruki Higashimori, Christina Schin, Alessandra Tamashiro Orrego, Yuqin Men, Ming Sum Ruby Chiang, Rachel Jarvis, Dan Cox, Larry A. Feig, Yongjie Yang

This study shows that astroglial FMRP loss affects synaptic signaling and behavioral phenotypes in FXS mice, with re-expression rescuing some deficits.

Glia · Sep 24, 2020Peer-reviewedNeuroscience