Author

Sébastien Lainé

Centre National de la Recherche ScientifiqueORCID 0000-0002-5217-4972Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Jérôme FeuillardiD· 1 shared Julie CoustoniD· 1 shared Mickaël BlaiseiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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1 shared paperMicrobiology

Jérôme FeuillardORCID

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1 paper

Recent·Most cited

Biochemical, structural, and functional characterization of the Nocardia asteroides dihydrofolate reductase: a primary target of anti-nocardiosis treatment

Julie Couston, Sébastien Lainé, Jérôme Feuillard, Mickaël Blaise

This study characterizes the biochemical and structural properties of Nocardia asteroides dihydrofolate reductase, showing its role in trimethoprim resistance and providing insights into drug binding mechanisms.

Biochimie · Oct 1, 2026Peer-reviewedMicrobiology