MicrobiologyBiochimiePeer-reviewed
Biochemical, structural, and functional characterization of the Nocardia asteroides dihydrofolate reductase: a primary target of anti-nocardiosis treatment
Julie Couston, Sébastien Lainé, Jérôme Feuillard, Mickaël Blaise
This study characterizes the biochemical and structural properties of Nocardia asteroides dihydrofolate reductase, showing its role in trimethoprim resistance and providing insights into drug binding mechanisms.
DOI 10.1016/j.biochi.2026.10.002