Author

Jian Huang

University of IowaORCID 0000-0002-5218-9269Unclaimed ORCID profile · follow to get notified of new preprints

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Jian Huang7 papers · Agency for Science, Technology and Research

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Research Focus:GWAS / association mapping· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:GWAS summary statistics· 1 Organism:human· 1 Approach:mixed model· 1

Frequent Co-Authors

Can YangiD· 2 shared Jin LiuiD· 2 shared Xingjie ShiiD· 2 shared Yi YangiD· 2 shared Yuling JiaoiD· 2 shared Haoyue CheniD· 1 shared Lei SuniD· 1 shared Min CheniD· 1 shared

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2019-2020 · peak 1/yr

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10 top collaborators · 39 mutual co-author links

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2 shared papersBioinformatics

Can YangORCID

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2 papers

Recent·Most cited

A tissue-specific collaborative mixed model for jointly analyzing multiple tissues in transcriptome-wide association studies

Xingjie Shi, Xiaoran Chai, Yi Yang, Qing Cheng, Yuling Jiao, Haoyue Chen, Jian Huang, Can Yang, Jin Liu

This paper introduces TisCoMM, a tissue-specific collaborative mixed model for TWAS that improves gene-trait association detection and identifies tissue-specific gene roles in complex traits.

Nucleic Acids Research · Sep 3, 2020Peer-reviewedBioinformatics

CoMM-S2: a collaborative mixed model using summary statistics in transcriptome-wide association studies

Yi Yang, Xingjie Shi, Yuling Jiao, Jian Huang, Min Chen, Xiang Zhou, Lei Sun, Xinyi Lin, Can Yang, Jin Liu

CoMM-S2 uses GWAS summary statistics to infer mechanistic roles of genetic variants in gene expression, achieving performance comparable to methods using individual-level data.

Bioinformatics · Nov 21, 2019Peer-reviewedBioinformatics