Construction of recombinant Bacillus subtilis spores surface-displaying PRRSV ORF1b, GP5, M, and N proteins in tandem and evaluation of their immunogenicity in mice
Yang Yang, Jianzhen Li, Pengfei Fang…·Kangcheng Pan
This study constructs a recombinant Bacillus subtilis spore displaying PRRSV proteins and evaluates its immunogenicity in mice, showing enhanced mucosal and systemic immune responses.