Parechovirus-3 infection disrupts immunometabolism and leads to glutamate excitotoxicity in neural organoids
Pamela E. Capendale, Anoop T. Ambikan, Inés García-Rodríguez, Renata Vieira de Sá, Dasja Pajkrt, Katja C. Wolthers, Ujjwal Neogi, Adithya Sridhar
This study identifies metabolic changes and glutamate excitotoxicity in HPeV-3 infected neural organoids, linking them to neuronal toxicity and apoptosis.
Cellular and Molecular Life Sciences · Nov 5, 2025Peer-reviewedNeuroscience