Author

Salvatore Simmini

ORCID 0000-0002-9366-3940Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:organoid / primary culture· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Allen C. Eaves· 2 shared Caroline TappareliD· 2 shared Georgios Stroulios· 2 shared Mathieu HubertiD· 2 shared Sharon A. Louis· 2 shared Wing Y. Chang· 2 shared Adithya SridhariD· 1 shared Alessandro Dei· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

Allen C. Eaves

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Human airway organoids as a high-throughput screening platform for antiviral natural products discovery

Mathieu Hubert, Paola Haemmerli, Laurence Marcourt, Emy Lara-Quintero, Loan Arthaud, Luis-Manuel Quirós-Guerrero, Sarah Donnaray, Katia Rimensberger, Arnaud Gaudry, Élodie Alessandri-Gradt, Georgios Stroulios, Yves Cambet, François Prodon, Bohumil Maco, Samuel Constant, , Caroline Tapparel

This study uses human airway organoids to screen 764 natural plant extracts for antiviral activity against RSV, identifying 45 active compounds with distinct mechanisms.

bioRxiv · Feb 4, 2026 · PreprintMicrobiology

Generation of apical-out nasal organoids to facilitate viral infection and drug screening

Georgios Stroulios, Mathieu Hubert, Wing Y. Chang, Allen C. Eaves, Sharon A. Louis, Philipp Krämer, Caroline Tapparel, Salvatore Simmini

This paper describes a method to generate apical-out nasal organoids from nasal epithelial cells, which can be used for studying viral infections and drug responses.

bioRxiv · Oct 7, 2025 · PreprintCell Biology

A Human Biomimetic Intestinal Mucosa Model to Study Gastrointestinal Development and Disease

Alessandro Dei, Carlemi Calitz, Joep Korsten, Nina Johannesson, Eline Freeze, Allen C. Eaves, Sharon A. Louis, Ryan K. Conder, Wing Y. Chang, Dasja Pajkrt, Katja C. Wolthers, Adithya Sridhar, Salvatore Simmini

This paper develops a human intestinal mucosa model incorporating epithelial, fibroblast, and antigen-presenting cells to study intestinal development and disease mechanisms.

bioRxiv · Aug 20, 2024 · PreprintCell Biology