Yijun Zhou

This study creates a vascularized bioengineered kidney using decellularized scaffolds recellularized with human placenta-derived angiogenic stem cells and kidney organoids, showing successful vascular and renal reconstruction in vivo.

The paper integrates human organoid scRNA-seq data with GWAS and gene-drug interaction data to identify cell type-specific drug targets for severe COVID-19.

The paper introduces scPagwas, a method that integrates pathway activation transformation of scRNA-seq data with GWAS summary statistics to identify trait-relevant cell populations and pathways.

The paper integrates GWAS and scRNA-seq data to identify genetics-influenced immune cell subpopulations associated with severe COVID-19, highlighting key cell types and genes involved in disease severity.