Yunlong Ma

scRBP infers cell-specific RNA-binding protein regulons from single-cell transcriptomes, resolving targets at gene and isoform levels and linking genetic risk to disease.

This study identifies three functional programs impacted by autism genes, contextualized across neuronal subclasses, developmental timing, and cortical regions.

The paper uses Mendelian randomization to identify causal relationships between gut microbes and diabetic retinopathy, finding that Streptococcus salivarius affects DR through host fasting glucose levels.

The paper integrates human organoid scRNA-seq data with GWAS and gene-drug interaction data to identify cell type-specific drug targets for severe COVID-19.

The paper introduces scPagwas, a method that integrates pathway activation transformation of scRNA-seq data with GWAS summary statistics to identify trait-relevant cell populations and pathways.

This study identifies low-frequency variants in FKBP5 and FOLH1 associated with high myopia in Han Chinese and European populations through whole-exome sequencing and functional experiments.

This study identifies 14 novel risk genes for oral cavity cancer, including IRF4, which is significantly associated with patient prognosis and potential drug repurposing.

The paper integrates GWAS and scRNA-seq data to identify genetics-influenced immune cell subpopulations associated with severe COVID-19, highlighting key cell types and genes involved in disease severity.

This study integrates GWAS summary statistics with single-cell RNA sequencing data to identify genetically influenced liver cell types associated with primary biliary cholangitis.

The paper identifies a novel 21q22.11 locus associated with COVID-19 susceptibility through GWAS and integrates eQTL data to show gene expression effects in lung tissue.