Author

Dong-Hua Chen

Stanford MedicineORCID 0000-0002-5247-0106Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:yeast· 1

Frequent Co-Authors

Heqiao ZhangiD· 1 shared Rayees U.H. MattooiD· 1 shared Roger D. KornbergiD· 1 shared Shigeki NagaiiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperBiochemistry

Heqiao ZhangORCID

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1 paper

Recent·Most cited

Reconstitution of +1 nucleosome transcription reveals coordinated functions of SAGA, Mediator, and TFIIH

Shigeki Nagai, Dong-Hua Chen, Rayees U.H. Mattoo, Heqiao Zhang, Roger D. Kornberg

This study reconstitutes transcription through the +1 nucleosome using purified yeast factors and finds that SAGA, Mediator, and TFIIH coordinate to overcome nucleosome barriers and regulate transcription initiation.

bioRxiv · Sep 28, 2026 · PreprintBiochemistry