Author
Stanford MedicineORCID 0000-0002-2425-7519Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
4 papers
Recent·Most cited
Andrey Feklístov, Roger D. Kornberg
The paper models human transcription factor activation domain-Tail module interactions of Mediator using AlphaFold 3 to understand how these interactions influence the Mediator-Pol II complex structure and transcriptional activation.
bioRxiv · Oct 5, 2026 · PreprintMolecular Biology
Shigeki Nagai, Dong-Hua Chen, Rayees U.H. Mattoo, Heqiao Zhang, Roger D. Kornberg
This study reconstitutes transcription through the +1 nucleosome using purified yeast factors and finds that SAGA, Mediator, and TFIIH coordinate to overcome nucleosome barriers and regulate transcription initiation.
bioRxiv · Sep 28, 2026 · PreprintBiochemistry
Adrian L. Sanborn, Benjamin T. Yeh, Jordan T. Feigerle, Cynthia V. Hao, Raphael J.L. Townshend, Erez Lieberman Aiden, Ron O. Dror, Roger D. Kornberg
The paper identifies 150 transcriptional activation domains in yeast, shows their binding to Mediator, and develops a neural network to predict ADs across species.
eLife · Apr 27, 2021Peer-reviewedMolecular Biology
Kyle P. Eagen, Erez Lieberman Aiden, Roger D. Kornberg
The paper identifies chromatin loops in Drosophila using Hi-C and finds that they are associated with Polycomb group proteins rather than CTCF, and are linked to gene repression.
Proceedings of the National Academy of Sciences · Aug 1, 2017Peer-reviewedMolecular Biology