Author

Kikuye Koyano

University of California, Los AngelesORCID 0000-0002-5250-9293Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:database / resource· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Xinshu Grace XiaoiD· 2 shared Feng GuoiD· 1 shared Ian BarriD· 1 shared Jae Hoon BahniD· 1 shared Jen Quick-ClevelandiD· 1 shared Jose P. Jacob· 1 shared Rachel Senturia· 1 shared Sara H. Weitz· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 29 mutual co-author links

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2 shared papersGenomics

Xinshu Grace XiaoORCID

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2 papers

Recent·Most cited

Extracellular microRNA 3' end modification across diverse body fluids

Kikuye Koyano, Jae Hoon Bahn, Xinshu Grace Xiao

The paper develops a method to identify 3' end modifications of miRNAs in extracellular biofluids and finds that uridylation levels distinguish biofluid types better than overall miRNA expression.

Epigenetics · Oct 23, 2020Peer-reviewedGenomics

Fe(III) heme sets an activation threshold for processing distinct groups of pri-miRNAs in mammalian cells

Sara H. Weitz, Jen Quick-Cleveland, Jose P. Jacob, Ian Barr, Rachel Senturia, Kikuye Koyano, Xinshu Grace Xiao, Shimon Weiss, Feng Guo

The paper investigates how Fe(III) heme availability affects pri-miRNA processing by DGCR8 and identifies a heme affinity threshold for Microprocessor activity.

bioRxiv · Feb 18, 2020 · PreprintMolecular Biology