Molecular BiologybioRxivPreprint
Fe(III) heme sets an activation threshold for processing distinct groups of pri-miRNAs in mammalian cells
Sara H. Weitz, Jen Quick-Cleveland, Jose P. Jacob…·Feng Guo
The paper investigates how Fe(III) heme availability affects pri-miRNA processing by DGCR8 and identifies a heme affinity threshold for Microprocessor activity.
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