A non-conventional archaeal fluorinase identified by in silico mining catalyzes the fastest natural nucleophilic fluorination
Isabel Pardo, David Bednář, Patricia Calero, Daniel C. Volke, Jiřı́ Damborský, Pablo I. Nikel
The paper identifies a novel archaeal fluorinase with the highest reported fluorination rate and demonstrates its application in enhancing fluoronucleotide production in bacterial hosts.
ACS Catalysis · May 19, 2022Peer-reviewedSynthetic Biology