Author

Ellis Patrick

The University of SydneyORCID 0000-0002-5253-4747Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 26 Immunology· 3 Neuroscience· 3 Cancer Biology· 2 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 23 Approach:statistical model· 20 Assay:spatial transcriptomics· 16 Research Focus:benchmarking· 13 Research Focus:differential expression· 11 Research Focus:cell type annotation· 10 Approach:deep learning· 9 Research Focus:gene regulatory network inference· 8

Frequent Co-Authors

Jean Yee Hwa YangiD· 15 shared Shila GhazanfariD· 8 shared Pengyi YangiD· 6 shared Elijah WillieiD· 5 shared Jinman KimiD· 5 shared Philip L. De JageriD· 5 shared Yingxin LiniD· 5 shared Andrew Nicholas HarmaniD· 4 shared

Activity by Year

2017-2026 · peak 7/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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15 shared papersBioinformatics

Jean Yee Hwa YangORCID

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Author profile →

35 papers

Recent·Most cited

BioinformaticsBioinformaticsPeer-reviewedAug 7, 2018

DCARS: Differential correlation across ranked samples

Shila Ghazanfar, Dario Strbenac, John T. Ormerod…·Ellis Patrick

DCARS identifies gene pairs with significant changes in correlation across survival stages, outperforming existing methods in cancer datasets.

8 citations

humanbulk RNA-seq

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Systems BiologyNature NeurosciencePeer-reviewedMay 21, 2018

A molecular network of the aging brain implicates INPPL1 and PLXNB1 in Alzheimer’s disease

Sara Mostafavi, Chris Gaiteri, Sarah E. Sullivan…·Philip L. De Jager

Molecular network analysis of RNA sequencing data from the aging human cortex identifies new Alzheimer's and cognitive decline genes.

509 citationstop 1%

humanbulk RNA-seq

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NeurosciencebioRxivPreprintDec 14, 2017

A cortical immune network map identifies a subset of human microglia involved in Tau pathology

Ellis Patrick, Marta Olah, Mariko F. Taga…·Philip L. De Jager

The paper identifies gene modules in human frontal cortex microglia associated with beta-amyloid and tau pathology in Alzheimer's disease.

12 citations

humanbulk RNA-seq

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BioinformaticsbioRxivPreprintJul 7, 2017

Brain xQTL Map: Integrating The Genetic Architecture Of The Human Brain Transcriptome And Epigenome

Bernard Ng, Charles C. White, Hans‐Ulrich Klein…·Philip L. De Jager

The paper identifies xQTLs in the human brain integrating RNA, DNA methylation, and histone acetylation data from 411 individuals, revealing 18 new CNS disease susceptibility loci.

39 citations

humanbulk RNA-seq

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NeuroscienceMolecular NeurodegenerationPeer-reviewedJul 1, 2017

Dissecting the role of non-coding RNAs in the accumulation of amyloid and tau neuropathologies in Alzheimer’s disease

Ellis Patrick, Sathyapriya Rajagopal, Hon Kit Wong…·Philip L. De Jager

The paper investigates the role of non-coding RNAs, specifically miRNAs and lincRNAs, in Alzheimer’s disease pathology by analyzing their expression in brain samples and integrating with mRNA data.

85 citationstop 3%

humanbulk RNA-seq

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