Author

Philippe Couttet

Novartis (Switzerland)ORCID 0000-0002-5255-6647Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Organism:human· 1 Organism:mouse· 1 Organism:non-human primate· 1

Frequent Co-Authors

Christian N. ParkeriD· 2 shared Alexander Bepperling· 1 shared Amanda Cobos‐Correa· 1 shared Angela Furrer· 1 shared Angelika S. MeyeriD· 1 shared Anne‐Christine UldryiD· 1 shared Arno DoelemeyeriD· 1 shared Aurelia Burget· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersPhysiology

Christian N. ParkerORCID

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3 papers

Recent·Most cited

Molecular BiologyMolecular Therapy — Methods & Clinical DevelopmentPeer-reviewedOct 17, 2025

Transcriptional changes in non-human primate tissues after intrathecal delivery of serotype 9 adeno-associated viral vector: insights into organ toxicities

Fumiaki Aihara, Mathew Mardo, Vera M. Ruda…·Eloïse Hudry

This study examines transcriptional changes in non-human primate tissues after AAV9 vector delivery, finding significant immune-related gene upregulation in liver and DRG.

1 citation

non-human primatebulk RNA-seq

𝕏 PostBluesky

PhysiologybioRxivPreprintApr 9, 2025

Exercise-Induced Myostimulin Enhances Muscle Function in Health and Disease

Frank Hillger, Keller Hansjörg, Angela Furrer…·Serge Summermatter

This study identifies myostimulin, a protein derived from C1ORF54, which enhances muscle function and recovery in mice, suggesting its potential as a therapeutic for musculoskeletal diseases.

DOI 10.1101/2025.04.09.647960

mousebulk RNA-seq

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Molecular BiologyCell ReportsPeer-reviewedAug 30, 2023

Drug-induced eRF1 degradation promotes readthrough and reveals a new branch of ribosome quality control

Lukas‐Adrian Gurzeler, Marion Link, Yvonne Ibig…·Jürgen Reinhardt

The paper introduces two novel readthrough promoters that induce eRF1 degradation, leading to PTC suppression and revealing a new ribosome quality control mechanism.

34 citations

humanproteomics

𝕏 PostBluesky