PathologybioRxivPreprint
Macrophage extracellular traps promote maladaptive cardiac remodelling and heart failure via PAD4-dependent mechanisms
Shohei Ichimura, Tomofumi Misaka, Satoshi Okochi…·Yasuchika Takeishi
This study shows that macrophage extracellular traps (METs) contribute to heart failure by promoting cardiac remodelling through PAD4-dependent mechanisms, and targeting METs may offer therapeutic potential.
DOI 10.64898/2026.03.15.711858