MicrobiologymBioPeer-reviewed
KSHV promotes oncogenic FOS to inhibit nuclease AEN and transactivate RGS2 for AKT phosphorylation
Vladimır Majerčiak, Beatriz Alvarado-Hernandez, Yanping Ma…·Zhi‐Ming Zheng
This study identifies KSHV ORF57 as a viral RNA-binding protein that stabilizes FOS RNA, inhibits AEN, and transactivates RGS2 to promote AKT phosphorylation during lytic infection.
7 citations