Maxine L. Wang

The paper identifies TXNDC15 as a regulator of ER membrane protein quality control, showing its dual role in modulating MARCHF6 activity and its link to ciliogenesis defects in Meckel-Gruber syndrome.

The paper describes an automated system for producing secreted proteins in transfected mammalian cells, enabling high-throughput, flexible, and cost-effective protein production for research.

The paper introduces a multiplex method to screen CSP extracellular interactions using nanoparticles and fluorescent beads, showing improved sensitivity and dynamic range over ELISA-based assays.

The paper introduces a dual sgRNA library design for CRISPRi screens to identify genetic modifiers, showing improved sensitivity and specificity in detecting epistatic relationships.