Cell BiologybioRxivPreprint
Pharmacologic eIF2B Activation Rescues Neuropathy in CMT2 Subtypes by Normalizing the Integrated Stress Response
Mary E. McMahon, Steve Lianoglou, Sridhar Narayan…·Paul R. August
RTX-117, a clinical stage eIF2B activator, blunts chronic ISR activation and improves nerve and motor function in a mouse model of Charcot-Marie-Tooth Disease Type 2D.
DOI 10.64898/2026.08.05.743063