β-catenin-dependent endomesoderm specification appears to be a Bilateria-specific co-option
Tatiana S. Lebedeva, Johan Boström, David Mörsdorf, Isabell Niedermoser, Evgeny Genikhovich, Igor I. Adameyko, Grigory Genikhovich
The paper shows that β-catenin signaling patterns the oral-aboral axis in Nematostella vectensis, but endoderm specification occurs opposite to nuclear β-catenin accumulation, suggesting this mechanism is a Bilateria-specific co-option.
bioRxiv · Oct 15, 2022 · PreprintDevelopmental Biology