Author

Christopher P. Loo

Oregon Health & Science UniversityORCID 0000-0002-5302-8774Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Abrar SamieaiD· 1 shared Adil E. WakiliD· 1 shared Alex G. Ortega‐LoayzaiD· 1 shared Alexis J. CombesiD· 1 shared Ann L. EricksoniD· 1 shared Arjun Arkal RaoiD· 1 shared Austin W. EdwardsiD· 1 shared Gabriela K. FragiadakisiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

Abrar SamieaORCID

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2 papers

Recent·Most cited

Clinical cure of chronic hepatitis B is dependent on activation and perpetuation of robust CD4+ T cell responses

Jillian M. Jespersen, Lia Avanesyan, Jean Publicover, Nicholas D. Carey, Ravi K. Patel, Austin W. Edwards, Sarah Stenske, Jae Hyun Shin, Jiajing Li, Margaret Simone, Nayvin W. Chew, Nicholas Wong, Suprita Trilok, Ann L. Erickson, Arjun Arkal Rao, , Jody L. Baron

The paper identifies shared mechanisms of HBsAg seroclearance using a mouse model and longitudinal PBMCs from CHB patients, showing CD4+ T cell activation is essential for clinical cure.

bioRxiv · Sep 29, 2025 · PreprintImmunology

IL-12/IL23 blockade reveals patterns of asynchronous inflammation in pyoderma gangrenosum

Rashi Yadav, Morgan Vague, Malia Rettig, Christopher P. Loo, Kasidy Brown, Abrar Samiea, Joshua Michael Moreau, Alex G. Ortega‐Loayza

This study uses spatial transcriptomics to analyze lesional skin from PG patients before and after IL-12/IL-23 blockade, revealing complex inflammation patterns and treatment-resistant B cell infiltration.

Journal of Investigative Dermatology · Oct 10, 2024Peer-reviewedImmunology