Cell BiologybioRxivPreprint
Oncogenic ERK signaling represses chaperone-mediated autophagy through transcriptional control of LAMP-2A
Eva Berenger, Merve Kacal, Alice Maestri…·Helin Vakifahmetoglu-Norberg
The paper identifies ERK signaling as a suppressor of chaperone-mediated autophagy (CMA) and shows that inhibiting ERK can restore CMA by increasing LAMP-2A expression.
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