This study evaluates the accuracy of genotype imputation for ancient genomes and finds it comparable to modern DNA, with some population-specific biases.

bioRxiv · Jul 19, 2022 · PreprintGenomics

Indigenous peoples in eastern Brazil: insights from 19th century genomes and metagenomes

Diana Ivette Cruz Dávalos, Yami Ommar Arizmendi Cárdenas, Miriam Bravo-Lopez, Samuel Neuenschwander, Silvia Reis, Murilo Bastos, Jesper T. Stenderup, Fulya Eylem Yediay, Viridiana Villa-Islas, Carlos S. Reyna-Blanco, Cláudia Rodrigues-Carvalho, Tábita Hünemeier, Morten E. Allentoft, Carlos Eduardo G. Amorim, J. Víctor Moreno-Mayar, , Anna‐Sapfo Malaspinas

The paper sequences 24 ancient Brazilian genomes, including 22 Botocudos, revealing Indigenous American ancestry without external gene flow and low heterozygosity, and identifies ancient pathogen lineages.

bioRxiv · Jan 27, 2022 · PreprintGenomics

The genetic origins of Saint Helena’s liberated Africans

Marcela Sandoval‐Velasco, Anuradha Jagadeesan, María C. Ávila‐Arcos, Shyam Gopalakrishnan, Jazmín Ramos‐Madrigal, J. Víctor Moreno-Mayar, Gabriel Renaud, Diana Ivette Cruz Dávalos, Erna Johannesdóttir, Judy Watson, Kate Robson-Brown, Andrew Pearson, Agnar Helgason, Marcus Thomas P. Gilbert, Hannes Schroeder

The paper uses ancient DNA analysis of 20 individuals from St Helena to determine the genetic origins of liberated Africans, finding they came from West Central Africa and were culturally diverse.

bioRxiv · Oct 1, 2019 · PreprintGenomics

In-solution Y-chromosome capture-enrichment on ancient DNA libraries

Diana Ivette Cruz Dávalos, María A. Nieves-Colón, Alexandra Sockell, G. David Poznik, Hannes Schroeder, Anne C. Stone, Carlos D. Bustamante, Anna‐Sapfo Malaspinas, María C. Ávila‐Arcos

This study applies Y-chromosome capture-enrichment to ancient DNA libraries, showing increased recovery of Y-DNA sequences and enabling haplogroup assignment.

BMC Genomics · Aug 14, 2018Peer-reviewedGenomics