Carlos Eduardo G. Amorim

The paper investigates Purkinje cell loss and genetic basis in spastic Han-Wistar rats, showing early-onset motor impairment and identifying potential causal mutations.

This study uses genomic data from Roman Dacia to show sex-biased ancestry patterns, indicating male-mediated gene flow and complex demographic interactions in Roman frontier communities.

This study analyzes ancient DNA from a rural English cemetery to explore genetic continuity and change following the Norman Conquest, finding no genome-wide discontinuity.

The paper tracks shifts in polygenic traits linked to infectious diseases across 10,000 years in Western Eurasia, showing associations with major historical epidemics.

This study examines the distribution of fitness effects (DFE) across eleven animal species, finding that DFE co-varies with phylogeny and that mammals have more deleterious mutations than insects and birds.

The paper compares the distribution of fitness effects of new amino acid changing mutations between dogs and wolves to assess the impact of domestication on selective pressures.

This study evaluates the accuracy of genotype imputation for ancient genomes and finds it comparable to modern DNA, with some population-specific biases.

The paper analyzes ancient genomic DNA from two cemeteries associated with the Longobards to study social organization and migration patterns in 6th-century Europe.

The paper examines the frequencies of recessive lethal mutations in human populations and finds they are higher than expected, suggesting ascertainment bias rather than mutation-selection balance.

The paper analyzes substitution rates across primate genomes and finds significant variation in molecular clocks between species and within hominoids, with CpG transitions showing more clock-like behavior.