Lan Luan

Learning induces activation-mechanism--dependent neural plasticity in an intracortical microstimulation task

Learning alters neural responses to ICMS, revealing differences between direct activation and network activity linked to behavior.

High-channel-count neural recording and stimulation platform with 5,376 simultaneous recording channels

This paper introduces a high-channel-count neural recording and stimulation platform with 5,376 channels, demonstrating its use in high-resolution cortical mapping in rat brains.

Temporal coding carries more stable cortical visual representations than firing rate over time

This study shows that temporal coding in visual cortical neurons provides more stable representations of visual stimuli over time compared to firing rate coding.

Low-threshold, high-resolution, chronically stable intracortical microstimulation by ultraflexible electrodes

This paper introduces ultraflexible electrodes that enable low-threshold, high-resolution, and chronically stable intracortical microstimulation in mice, with no neuronal degeneration or glial scarring observed.

Longitudinal neural and vascular recovery following ultraflexible neural electrode implantation in aged mice

This study examines neural and vascular recovery in aged mice after ultraflexible electrode implantation, finding vascular remodeling precedes neural signal recovery and normalizes by six weeks.

Dynamics of isoflurane-induced vasodilation and blood flow of cerebral vasculature revealed by multi-exposure speckle imaging

This study uses multi-exposure speckle imaging to show that isoflurane anesthesia causes rapid and sustained increases in cerebral vessel diameter and blood flow in mice.

Multimodal mapping of neural activity and cerebral blood flow reveals long-lasting neurovascular dissociations after small-scale strokes

This study uses a multimodal platform in mice to track neural activity and cerebral blood flow after small strokes, revealing long-lasting neurovascular dissociations.