Saumil Surendra Patel

Stable, chronic in-vivo recordings from a fully wireless subdural-contained 65,536-electrode brain-computer interface device

This paper presents a high-bandwidth, wireless brain-computer interface device capable of chronic recordings in animals, demonstrating reliable performance over weeks.

Beyond retinotopy: exploiting native visual representations in cortical neuroprostheses for vision loss remediation

This paper improves visual prosthetics by incorporating orientation selectivity with retinotopy to better match natural neural responses in the visual cortex.

Temporal coding carries more stable cortical visual representations than firing rate over time

This study shows that temporal coding in visual cortical neurons provides more stable representations of visual stimuli over time compared to firing rate coding.

Dual-feature selectivity enables bidirectional coding in visual cortical neurons

The paper identifies a dual-feature encoding strategy in visual cortical neurons where neurons respond to both enhancing and suppressing visual features, showing this strategy is conserved across species.

NEURD offers automated proofreading and feature extraction for connectomics

NEURD automates proofreading and feature extraction from connectomics data to improve accuracy and accessibility of neural morphology analyses.

Functional connectomics spanning multiple areas of mouse visual cortex

The paper presents a functional connectomics dataset of mouse visual cortex, combining calcium imaging with EM reconstruction to study neural circuits and their connectivity.

Functional connectomics reveals general wiring rule in mouse visual cortex

Functionally similar neurons in mouse visual cortex connect preferentially across layers and areas, including feedback, and feature tuning, not receptive-field position, predicts synapses beyond axon-dendrite proximity.

Deep learning-driven characterization of single cell tuning in primate visual area V4 supports topological organization

The paper uses deep learning to analyze single-cell neural responses in primate visual area V4, finding functional clustering that mirrors artificial vision systems.

Foundation model of neural activity predicts response to new stimulus types and anatomy

This paper trains a foundation model on neural activity data to predict responses to new stimuli and anatomical features, showing strong generalization across mice and tasks.

Bipartite invariance in mouse primary visual cortex

The paper identifies a novel bipartite invariance in mouse V1 neurons, where receptive fields encode shift-invariant high-frequency textures and fixed low-frequency patterns, contributing to segmentation.

Pattern completion and disruption characterize contextual modulation in the visual cortex

The paper uses CNNs to analyze contextual modulation in visual cortex by synthesizing surround patterns, finding that pattern completion enhances responses while disruption suppresses them, consistent across mice and macaques.

Cellular and Circuit Organization of the Locus Coeruleus of Adult Mice

The paper investigates the local circuit organization of noradrenergic neurons in the locus coeruleus of adult mice, revealing diverse morpho-electric types and chain-like electrical coupling patterns.

Energy Guided Diffusion for Generating Neurally Exciting Images

This paper introduces Energy Guided Diffusion (EGG) to generate neurally exciting images, outperforming gradient ascent in generalization and efficiency for macaque V4 models.

Behavioral state tunes mouse vision to ethological features through pupil dilation

The paper shows that pupil dilation in mice shifts color selectivity in the visual cortex towards ultraviolet stimuli, enhancing detection of ethological features like aerial predators.

Petascale neural circuit reconstruction: automated methods

Cloud-run convolutional nets aligned 19,939 serial EM sections of mouse visual cortex despite cracks and folds, segmented neurons and detected 523 million synapses; code and the reconstruction are public.

Object manifold geometry across the mouse cortical visual hierarchy

Recordings of thousands of mouse visual cortex neurons reveal that lateral areas LM, LI, and AL carry higher linearly decodable object information associated with reduced object manifold dimension and radius.

Neocortical layer 4 in adult mouse differs in major cell types and circuit organization between primary sensory areas

The paper identifies distinct cell types and circuit organization in layer 4 of primary sensory areas in adult mouse neocortex, challenging the canonical microcircuit model.

Faster processing of moving compared to flashed bars in awake macaque V1 provides a neural correlate of the flash lag illusion

The paper shows that moving bars are processed faster than flashed bars in macaque V1, supporting the differential latency model of the flash lag illusion.