Molecular BiologybioRxivPreprint
The LacI hinge region balances binding stability against inducibility
Jinwen Yuan, Malin Lüking, Spartak Zikrin…·Johan Elf
This study investigates how mutations in the hinge region of LacI affect binding stability and inducibility, showing a trade-off between binding strength and inducibility rather than speed and stability.
DOI 10.1101/2025.05.07.652604