Emil Marklund

This study links in vitro transcription factor affinities to in vivo single-molecule chromatin states using thermodynamic models and experimental data for KLF1.

This study investigates how mutations in the hinge region of LacI affect binding stability and inducibility, showing a trade-off between binding strength and inducibility rather than speed and stability.

This study links transcription factor binding to gene expression by analyzing chromatin configurations using single-molecule footprinting in human cells.

This study measures the rotation-coupled diffusion of LacI along DNA, finding it moves ~50 base pairs per revolution, supporting a facilitated diffusion model.