Author

Jessica A. Scarborough

Cleveland ClinicORCID 0000-0002-5365-5735Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Approach:statistical model· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Jacob G. ScottiD· 2 shared Andrew DhawaniD· 1 shared Davis T. WeaveriD· 1 shared Drew F. K. WilliamsoniD· 1 shared Kathleen I. PishasiD· 1 shared Kristi Lin‐RahardjaiD· 1 shared Stephen L. Lessnick· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 16 mutual co-author links

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2 shared papersCancer Biology

Jacob G. ScottORCID

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2 papers

Recent·Most cited

Cancer BiologyPLoS Computational BiologyPeer-reviewedSep 10, 2025

Personalizing chemotherapy drug selection using a novel transcriptomic chemogram

Kristi Lin‐Rahardja, Jessica A. Scarborough, Jacob G. Scott

This paper introduces a framework called the chemogram to rank drug sensitivity using transcriptomic signatures, showing improved accuracy over random predictions for multiple chemotherapy drugs.

2 citations

humanbulk RNA-seq

𝕏 PostBluesky

Systems BiologyPLoS Computational BiologyPeer-reviewedOct 18, 2021

Network potential identifies therapeutic miRNA cocktails in Ewings Sarcoma

Davis T. Weaver, Kathleen I. Pishas, Drew F. K. Williamson…·Jacob G. Scott

This paper identifies therapeutic miRNA cocktails for Ewing Sarcoma using a network science-based approach to prioritize miRNA targets and combinations.

15 citations

humanbulk RNA-seq

𝕏 PostBluesky