Systems BiologyPLoS ONEPeer-reviewed
Higher order synthetic lethals are keys to minimize cancer treatment effects on non-tumor cells
Mehdi Dehghan Manshadi, Payam Setoodeh, Amin Ramezani…·Habil Zare
This study identifies strictly-selective drug targets for 13 cancers using higher-order synthetic lethal sets to minimize harm to non-tumor tissues.
2 citations