IGF1 modulates lesional skin inflammation in checkpoint inhibitor-induced lichen planus
Noah I. Hornick, Avery Billo, Rosalyn M. Fey, Reed M. Hawkins, Fiorinda F. Muhaj, Kristen N. Richards, Anisha B. Patel, Jason M. Schenkel, Kristen E. Pauken, Amy E. Moran
This study identifies distinct transcriptional features in fibroblasts and myeloid cells of ICI-LP compared to LP, highlighting differences in IGF1, JAK-STAT, and interferon pathways.
bioRxiv · May 28, 2026 · PreprintImmunology