Jason M. Schenkel

IGF1 modulates lesional skin inflammation in checkpoint inhibitor-induced lichen planus

This study identifies distinct transcriptional features in fibroblasts and myeloid cells of ICI-LP compared to LP, highlighting differences in IGF1, JAK-STAT, and interferon pathways.

Lymph node resident memory T cells retain effector capabilities by evading lung resident memory dysfunction.

This study identifies lymph node resident memory T cells (LNRM) as a distinct subset with unique effector capabilities compared to lung resident memory T cells and central memory T cells.

In vivo antibody labeling route and fluorophore dictate labeling efficiency, sensitivity, and longevity

This study shows that changing antibody administration route and fluorophore improves leukocyte labeling efficiency, sensitivity, and duration for tracking migration.

Single-nucleus and spatial transcriptomics of archival pancreatic cancer reveals multi-compartment reprogramming after neoadjuvant treatment

This study uses single-nucleus and spatial transcriptomics to analyze pancreatic cancer before and after neoadjuvant treatment, revealing changes in cell states and immune infiltration that may inform therapy.