Author

Daniela Lazzaretti

University of RegensburgORCID 0000-0002-5372-9343Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:protein structure· 2 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Jobst LiebauiD· 2 shared Remco SprangersiD· 2 shared Till RudackiD· 2 shared Anna BichleriD· 1 shared Aysa Yelboga· 1 shared David StelzigiD· 1 shared Kresten Lindorff‐LarseniD· 1 shared Matteo CagiadaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiophysics

Jobst LiebauORCID

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2 papers

Recent·Most cited

Nanosecond methyl dynamics in the eukaryotic RNA exosome core

Daniela Lazzaretti, Matteo Cagiada, Aysa Yelboga, David Stelzig, Kresten Lindorff‐Larsen, Till Rudack, Remco Sprangers, Jobst Liebau

This study uses NMR to measure nanosecond methyl dynamics in the RNA exosome core, showing that relaxation-violated coherence transfer experiments can quantify side chain order parameters in large protein complexes.

bioRxiv · Jul 25, 2026 · PreprintBiophysics

4D structural biology: quantitative dynamics in the eukaryotic RNA exosome complex

Jobst Liebau, Daniela Lazzaretti, Torben F. Fürtges, Anna Bichler, Michael Pilsl, Till Rudack, Remco Sprangers

The paper uses NMR and simulations to study dynamic motions in the eukaryotic RNA exosome complex, revealing conformational changes and a flexible plug region that blocks RNA pathways.

Nature Communications · Aug 24, 2025Peer-reviewedMolecular Biology