Author

Dorka Nagy

Imperial College LondonORCID 0000-0002-5373-9664Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genetic & Genomic Medicine· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:ChIP-seq· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Inês CebolaiD· 2 shared Aaron LeongiD· 1 shared Ahmed N. AlkanaqiD· 1 shared Aida Martínez-SáncheziD· 1 shared Alessandra Pisante· 1 shared Alicia Huerta‐ChagoyaiD· 1 shared Alisa Knodle ManningiD· 1 shared Anna L. GloyniD· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Inês CebolaORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Genetic & Genomic MedicineNature GeneticsPeer-reviewedOct 8, 2024

Rare variant association analysis in 51,256 type 2 diabetes cases and 370,487 controls informs the spectrum of pathogenicity of monogenic diabetes genes

Alicia Huerta‐Chagoya, Philip H. Schroeder, Ravi Mandla…·Josep Maria Mercader

The paper conducts a large-scale rare variant GWAS meta-analysis of type 2 diabetes, identifying novel variants in monogenic diabetes genes and assessing their pathogenicity.

39 citationstop 1%

humanwhole-genome sequencing

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Cell BiologyThe FASEB JournalPeer-reviewedAug 14, 2024

Liver kinase B1 (LKB1) regulates the epigenetic landscape of mouse pancreatic beta cells

Nejc Haberman, Rebecca Cheung, Grazia Pizza…·Aida Martínez-Sánchez

This study shows that LKB1 deletion in mouse pancreatic beta cells causes widespread chromatin accessibility changes and affects gene expression, including neuronal genes.

4 citations

mouseChIP-seq

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GenomicsNucleic Acids ResearchPeer-reviewedJul 11, 2023

Identification of mammalian transcription factors that bind to inaccessible chromatin

Romana T Pop, Alessandra Pisante, Dorka Nagy…·Nicolae Radu Zabet

The paper develops a statistical model to predict TF binding to chromatin and finds that about one third of TFs bind independently of chromatin accessibility.

28 citations

humanmouse

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