Author

Rebecca Cheung

Imperial College London

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Molecular Biology· 2 Cell Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Aida Martínez-SáncheziD· 3 shared Guy A. RutteriD· 3 shared Boris LenhardiD· 2 shared Grazia Pizza· 2 shared Nejc HabermaniD· 2 shared PAULINE L. CHABOSSEAUiD· 2 shared Alejandra TomásiD· 1 shared Andrew M JobbinsiD· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMolecular Biology

Aida Martínez-SánchezORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Abundant capped RNAs are derived from mRNA cleavage at 3'UTR G-Quadruplexes

Nejc Haberman, Holly Digby, Rupert Faraway, Rebecca Cheung, Anob M. Chakrabarti, Andrew M Jobbins, Callum Parr, Kayoko Yasuzawa, Takeya Kasukawa, Chi Wai Yip, Masaki Kato, Hazuki Takahashi, Piero Carninci, Santiago Vernia, Jernej Ule, , Boris Lenhard

The paper identifies 3UTR-derived capped RNAs, showing they are abundant and originate from AGO2-mediated cleavage at G-quadruplexes, with implications for APP protein regulation.

BMC Biology · Nov 7, 2024Peer-reviewedMolecular Biology

Liver kinase B1 (LKB1) regulates the epigenetic landscape of mouse pancreatic beta cells

Nejc Haberman, Rebecca Cheung, Grazia Pizza, Nevena Cvetešić, Dorka Nagy, Hannah Maude, Lorea Blázquez, Boris Lenhard, Inês Cebola, Guy A. Rutter, Aida Martínez-Sánchez

This study shows that LKB1 deletion in mouse pancreatic beta cells causes widespread chromatin accessibility changes and affects gene expression, including neuronal genes.

The FASEB Journal · Aug 14, 2024Peer-reviewedCell Biology

Glucose-dependent miR-125b is a negative regulator of β-cell function

Rebecca Cheung, Grazia Pizza, PAULINE L. CHABOSSEAU, Delphine Rolando, Alejandra Tomás, Thomas Burgoyne, Zhiyi Wu, Anna Sałówka, Anusha Thapa, Annabel Macklin, Yufei Cao, Marie‐Sophie Nguyen‐Tu, Matthew T. Dickerson, David Aaron Jacobson, Piero Marchetti, , Aida Martínez-Sánchez

This study identifies miR-125b-5p as a glucose-regulated miRNA that negatively regulates β-cell function by modulating organelle dynamics and insulin secretion.

Diabetes · Apr 27, 2022Peer-reviewedMolecular Biology

Loss of ZnT8 function protects against diabetes by enhanced insulin secretion

Om Prakash Dwivedi, Mikko Lehtovirta, Benoît Hastoy, Vikash Chandra, Nicole A. J. Krentz, Sandra Kleiner, Deepak Jain, Ann-Marie T. Richard, Fernando Abaitua, Nicola L. Beer, Antje K. Grotz, Rashmi B. Prasad, Ola Hansson, Emma Ahlqvist, Ulrika Krus, , Leif Groop

The paper shows that a loss-of-function variant in ZnT8 improves insulin secretion and protects against type 2 diabetes by enhancing glucose responsiveness and proinsulin conversion.

Nature Genetics · Nov 1, 2019Peer-reviewedGenetics