Author

Chris Y. H. Chiu

St Vincents Institute of Medical ResearchORCID 0000-0002-5380-1114Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Abby FosteriD· 1 shared Alan F. RubiniD· 1 shared Daniel V. BrowniD· 1 shared Eleonora TresoldiiD· 1 shared Fergus J. CameroniD· 1 shared Jianan WangiD· 1 shared John A. KarasiD· 1 shared Laura B. KingiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

Abby FosterORCID

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2 papers

Recent·Most cited

CMDdemux: an efficient single cell demultiplexing method

Jianan Wang, Lizhong Chen, Daniel V. Brown, Chris Y. H. Chiu, Terence Paul Speed

CMDdemux improves single-cell demultiplexing accuracy by integrating hashing and mRNA data, outperforming existing methods on both high- and low-quality datasets.

Nucleic Acids Research · Apr 23, 2026Peer-reviewedBioinformatics

Proinsulin C-peptide is a major source of HLA-DQ8 restricted HIPs recognized by human Islet-Infiltrating CD4+ T cells

Pushpak Bhattacharjee, Miha Pakusch, Matthew Lacorcia, Eleonora Tresoldi, Alan F. Rubin, Abby Foster, Laura B. King, Chris Y. H. Chiu, Thomas W. H. Kay, John A. Karas, Fergus J. Cameron, Stuart I. Mannering

This study identifies 13 new proinsulin-derived HIPs recognized by human islet-infiltrating CD4+ T cells in T1D, highlighting proinsulin C-peptide's central role in HIP formation.

PNAS Nexus · Oct 30, 2024Peer-reviewedImmunology